Bioinformatics aims to understand the information entailed in biological molecules and structures. Given the sheer size of data generated by genome sequencing projects bioinformatics is intimately intertwined with another branch of informatics, i.e. computer sciences. Based on two wet labs geared towards analyzing their own DNA (isolation and amplification of the mitochondrial DNA control region and of PV92, a polymorphic locus on chromosome 16) workshop participants explore the realm of this exciting new field, combining wet-lab-based DNA analysis with computer-based bioinformatics modules.

The objectives of the course are:

1. Teach educators principles, tools, applications of genomics, proteomics, and bioinformatics
2. Introduce to educators modules that can be taught
3. Empower educators to develop their own lessons
4. Help educator's improve their skills in handling computers

The flow of the course follows this outline:

1. Sequence basics: random vs. biological sequences
2. Sequence patterns in genes
3. Identifying genes in sequences
4. Identifying genes in databases
5. Identifying and working with human genetic variation; phylogenetic trees
6. Genes, proteins, and diseases

The ratio of computer labs vs. wet labs vs. lectures is about 10:3:5. Through guided computer exercises course participants use online tools for DNA analysis, database searches, and genomic browsers, building a basic understanding of bioinformatics-specific analysis routines and how they are rooted in molecular biology and genetics.

Over the course of the workshop participants more and more self-sufficiently tackle computer-based problems, that have been developed in order to foster bioinformatics and computer skill development and to initiate teacher's thinking about how to integrate bioinformatics into their own teaching.