Bioinformatics

8/11/01

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Table of Contents

Human (H. sapiens): 35,000

Exon skipping mutations in A. thaliana: splicing in multi-intron pre-mRNA may be affected by other introns in transcript

A Dynamic Concept

One Gene - One Transcript

Current consensus

Sources of Complexity

Lots of data that need to be

Multiple Alignment

Protein domains

Databases contain more than just DNA & protein sequences

Biology vs. Informatics

Finding Genes in Human Genome Sequence Not Easy

It’s all about patterns

Cut/End Part One***

Author: DNA Learning Center