Professor David Van Vactor describes how axons grow during neurodevelopment.
Axons navigate across long distances to reach their targets in the nervous system very much like a driver navigating to a distant destination without having ever seen the terrain. They express a defined set of receptor molecules that essentially give them a way of reading road signs along the way to their targets, but they rely upon these signposts along the way in order to make those decisions and choose the correct path.
axon, growth, guidance, neurodevelopment, development, receptor, molecules, david, van, vactor
L1 cell adhesion molecule (L1CAM), also known as neural cell adhesion molecule 1 or A0290, is a member of a subgroup of integral membrane proteins that belong to the immunoglobulin superfamily cell adhesion molecules (CAM).