Growth Cones (2)

Professor David Van Vactor discusses how growth cones read molecular 'signposts,' which help axons find the correct path.

So, the growth cone expresses on its surface a variety of receptors that allow the growth cone to recognize both attractive and repellent cues - stop signs and green lights in the embryonic environment. And these guideposts are there to give the growth cone signals that will define its path. But in order to find the correct path, the growth cone has to respond correctly to those signals and translate the stop and the go signal into forward movement or avoidance.

growth, cones, axon, guidance, signpost, neurodevelopment, receptor, signal, signaling, van vactor

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