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ID 1242
Translocation
Description:
Professor David Porteous explains that a translocation is the relocation of part of one chromosome to a another chromosome.
Transcript:
Translocation, if we break down the word, means "trans" - across, and "location" - place. So what that means for a human geneticist or a cytogeneticist, is that there has been a breakage and rejoining of two bits of the human genome in the form of chromosomes. So, to give you a specific example, if we have a translocation between human chromosomes 1 and 11, that means there's been a break on human chromosome number 1 and a break on human chromosome number 11; and a bit of chromosome 1 has transferred to the chromosome 11, and the reciprocal event a bit of chromosome 11 is transferred to the chromosome 1. That, in essence, is what we mean by a translocation.
Keywords:
translocation, location, transfer, chromosome, cytogeneticist, geneticist, genetic, genomic, genome, david, porteous
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This work by Cold Spring Harbor Laboratory is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.Related content:
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