Interviewee: Paul Berg.
Paul Berg speaks about Herbert Boyer's research into the process by which an organism, such as a bacterium, can recognize and destroy foreign DNA.
(DNAi Location: Manipulation > Techniques > Cutting & Pasting > Interviews > On the phenomenon of restriction)
Boyer, Herb Boyer had been studying restriction, the phenomenon of restriction. And he, along with a few others, realized and discovered that restriction, restriction was defined as if you took DNA from one organism and put it into another they destroyed it. But if you took their own DNA and put it in, it went in and survived, so there, there had to be some way in which a given organism recognized its own DNA and also recognized somebody else's DNA as being foreign and destroyed it.
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Paul Berg's student, Janet Mertz, planned an experiment that would recombine DNA from a monkey virus with DNA from a bacterium that lives in the human gut. Berg describes colleague Bob Pollack's outrage at this.