Interviewee: Bud and Yvonne. CML causes an increased production of white blood cells. Bud and Yvonne talk about the breakthrough that brought Bud's white blood cell count back to normal. (DNAi Location: Applications > Genes and medicine > drug design > Bud's Story > A Breakthrough)

Yvonne: Okay this is a chart of blood – white blood counts that was taken – this is about a year before he started, at that time it was known as STI-571. Bud: Yes that's it. Yvonne: And he was in the 35/50,000 range. 60,000. Bud: White blood count. Yvonne: And the white blood count which is normally I think it's about 10,000 is about the highest a person would get on it. Then he started taking this STI-571 which is Gleevec™ and about 17 days he was back down into his normal range on his white blood count and he's been normal ever since. And this is just what an important thing – what a breakthrough, I don't know what else to call it.

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