Website Search
ID 15048

Better diagnosis, David Botstein

Description:
Interviewee: David Botstein. David Botstein talks about the goal of using microarray analysis to improve cancer diagnosis. (DNAi Location: Applications > Genes and medicine > Genetic profiling > David Botstein > Better diagnosis)
Transcript:
You can imagine that we can identify proteins that, on the basis of over expression of their RNA, which is what we measure, that might be detected in the circulation when people have cancer and yet, as yet don't have symptoms. And it is a longer term goal of ours to make that into a reality. There's every theoretical reason for believing that that can be done and there are examples that already exist, for example the PSA for prostate cancer is such a test. And it's enormously valuable in the management of the disease.
Keywords:
david botstein,cancer proteins,cancer diagnosis,genetic profiling,theoretical reason,location applications,dnai,gene expression,prostate cancer,interviewee,term goal,rna,psa,genes,circulation,medicine
Downloads:
Creative Commons License This work by Cold Spring Harbor Laboratory is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.

Related content:

15046. Better cancer therapies by identifying oncogenes, David Botstein
David Botstein discusses how identifying the molecular mechanisms of cancer will lead to the development of improved therapies.
15047. Promises of genomics, David Botstein
David Botstein (sitting with Pat Brown) talks about how innovations in genomics might lead to personalized medicine.
15045. Why tumor typing is important, David Botstein
David Botstein talks about how tumor typing using genome-wide analysis will help doctors determine the most appropriate treatments for their patients.
15040. Using DNA microarrays to study cancer, Patrick Brown
Pat Brown talks about using microarrays to discover the differences between cancer cells and healthy cells.
15053. Gene profile and response to treatment, Stephen Fodor
Stephen Fodor talks about how an individual's gene expression profile can help determine what therapies might work best.
15244. Why he formed Myriad, Mark Skolnick
Mark Skolnick talks about forming a company to discover genes and develop genetic tests.
15249. Utah's resource, Mark Skolnick
Mark Skolnick talks about taking advantage of the well-documented genealogy of the Mormon pioneers to study inherited genetic disorders.
15126. Using pedigress in the hunt for BRCA1, Mary-Claire King
Mary-Claire King talks about the value of using the centuries-old tool of family pedigrees to gain insight into patterns of inheritance of genetic disorders.
15082. Shutting down cancer with Gleevec, Brian Druker
Brian Druker reflects on the importance of understanding the causes of cancer for developing new treatments.
15124. Better treatment for breast cancer, Mary-Claire King
Mary-Claire King reflects on how knowledge gained from the identification of BRCA1 and BRCA2 could lead to improved cancer treatments.
Cold Spring Harbor Laboratory
CSHL HomeAbout CSHLResearchEducationNews & FeaturesCampus & Public EventsCareersGiving