Website Search
ID 15067

Promises of gene therapy, Mario Capecchi

Description:
Interviewee: Mario Capecchi. Mario Capecchi talks about the possible use of embryonic stem cells and gene targeting techniques to develop new therapies for for diabetes and Parkinson's. (DNAi Location: Applications > Genes and Medicine > Gene targeting > Possibilities > Possibilities for new therapies)
Transcript:
And the question is, what should you be able to do then, because they show enormous promise in terms of therapeutic, for example somebody that doesn't have the islet cells which are capable of making insulin, they have diabetes, and the question is can you use these cells then to reimplant into the pancreas and thereby regenerate essentially a functional pancreas. Alternatively, there are diseases of the brain, Parkinson disease where particular cells are dying, and these cells may be able to be implanted into the brain and they will then participate in making brain tissues, and thereby then getting around the problem of Parkinson.
Keywords:
embryonic stem cells,brain parkinson,mario capecchi,diseases of the brain,brain tissues,islet cells,enormous promise,location applications,dnai,gene therapy,interviewee,pancreas,insulin,genes,promises,possibilities,diabetes,medicine
Downloads:
Creative Commons License This work by Cold Spring Harbor Laboratory is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.

Related content:

15059. Gene targeting, Mario Capecchi
Mario Capecchi talks about manipulating embryonic stem (ES) cells to make specific mutations in mouse embryos.
15070. An artificial chromosome?, Mario Capecchi
Mario Capecchi talks about the possibility of introducing an artificial chromosome into cells to slow the aging process.
15069. Gene therapy (germ line), Mario Capecchi
Mario Capecchi discusses the idea that someday therapies may be created to correct defective genes in egg and sperm cells.
15068. Gene therapy (somatic cell), Mario Capecchi
Mario Capecchi talks about the possibility of correcting genetic defects.
15060. Homologous recombination, Mario Capecchi
Mario Capecchi discusses homologous recombination, the technique he developed to introduce a desired mutation into the DNA of living cells.
15061. Technique to control a gene (Part I), Mario Capecchi
Mario Capecchi explains the technique he uses to control genes in mice.
15062. Technique to control a gene (Part 2), Mario Capecchi
Mario Capecchi continues his explanation of the technique he uses to control genes in mice.
838. Stem Cell Possibilities
Research continues to show that stem cells could be harnessed for therapeutic purposes.
16106. Approaches to making new therapies, Mario Capecchi
Mario Capeccchi talks about approaches to making new therapies.
15707. Mice used as model organisms
Gene targeting techniques are used by scientists to simulate human genetic disorders in model organisms. Many scientists believe that gene targeting will lead the way to new methods for correcting genetic defects.
Cold Spring Harbor Laboratory
CSHL HomeAbout CSHLResearchEducationNews & FeaturesCampus & Public EventsCareersGiving