Audacious idea of sequencing the human genome?, Leroy Hood
Description:
Interviewee: Leroy Hood.
Audacious idea of sequencing the human genome ?
Transcript:
Well if you think about the most important observation that came out of Watson and Crick's structure of DNA, it is that DNA is a digital code, a code that's embedded on 24 digital strings in the human. And the idea that you could actually read out the digital information that was the very core source code for human development, was an enormously exciting idea. And up until that time people tended to think much more in terms of maybe we can sequence very, very small genes if we spend a lot of time working. But the audacious idea that you could sequence many genes and even more important ultimately that you could sequence the entire genome, moved our ability to think about deciphering the digital information of our chromosomes in a very, very different direction.
Keywords:
human genome project,watson and crick,jim watson,leroy hood,james watson,dna code,structure of dna,project genome,interviewee,digital information,chromosomes,genes,source code,observation
James Watson and Francis Crick solved the structure of DNA. Other scientists, like Rosalind Franklin and Maurice Wilkins, also contributed to this discovery.
James Watson describes sequencing the human genome using markers and BACs, and Craig Venter explains using cDNA libraries, ESTs, and shotgun sequencing.