Website Search
ID 15306

The difficulties of DNA assembly, Jim Kent

Description:
Interviewee: Jim Kent. The difficulties of DNA assembly.
Transcript:
What makes DNA assembly maybe more challenging even than Russian prose is that it can actually be read forward and backwards, and so you have to see if it goes this way, or and if it doesn't go this way, maybe it goes that way. And this, this bit actually was, was particularly hard for me because I had a little bit of dyslexia when I was a kid and I was always getting my letters reversed. And so does it go this way or that way and I don't know it was kind of confusing too. I would all the time be getting things backwards and would just have to proceed by trial and error. Fortunately there would be only two cases, you know, if it wasn't this way then, well, just swap the sign and maybe it'll work that way.
Keywords:
russian prose,jim kent,dna sequencing,interviewee,dyslexia,trial and error,berkeley,little bit
Downloads:
Creative Commons License This work by Cold Spring Harbor Laboratory is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.

Related content:

15314. Genome assembly, repeats, and reading the genome, Jim Kent
Jim Kent, the author of the assembly program for the public sequence, talks about the difficulties of reassembling small pieces of the genome when there are so many repeat sequences.
16121. A farm of computers, Jim Kent
Jim Kent talks about a farm of computers.
15307. The data structure of the human genome: poetry or prose?, Jim Kent
Jim Kent talks about the data structure of the human genome: poetry or prose?
15305. Compiling the data from the Human Genome Project, Jim Kent
Jim Kent, the author of the assembly program for the public sequence, talks about the challenge of reassembling the genome.
15309. Junk DNA in the human genome, Jim Kent.
Jim Kent talks about junk DNA in the human genome.
15310. Cell division and DNA, Jim Kent
Jim Kent talks about cell division and DNA.
15304. Dealing with sequencing data, Jim Kent
Jim Kent talks about dealing with sequencing data.
15311. Telomeres and cell death, Jim Kent
Jim Kent talks about telomeres and cell death.
15289. Translating the genome and Russian prose, Ewan Birney
Ewan Birney, a key figure in the public sequence analysis, talks about trying to find meaning in the sequence.
15312. Banding appears in dyed chromosomes, Jim Kent
Jim Kent talks about banding appears in dyed chromosomes.
Cold Spring Harbor Laboratory
CSHL HomeAbout CSHLResearchEducationNews & FeaturesCampus & Public EventsCareersGiving