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ID 15356
Determining the nucleotide sequences of all RNA codons, Marshall Nirenberg
Description:
Interviewee: Marshall Nirenberg.
Marshall Nirenberg talks about Gobind Khorana, who synthesized many of the triplets needed to finish the decoding process.
(DNAi Location: Code > Reading the code > Players > Har Gobind Khorana >Finishing the code)
Transcript:
Gobind Khorana is, was at that time the, one of the world's best organic chemists working in the field of nucleic acids, highly experienced and superbly equipped to do this. He synthesized the 64 triplets chemically and he also synthesized repeating polymers with known doublets, repeating doublets or triplets as well, and towards the end he used them all to determine nucleotide sequences also. So between the two labs, he used the ribosome binding assay that we had established and between the two labs we determined all of the nucleotide sequences of RNA codons.
Keywords:
rna codons,har gobind khorana,nucleotide sequences,organic chemists,marshall nirenberg,nucleic acids,dnai,amino acids,cracking the code,location code,interviewee,triplets,polymers
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This work by Cold Spring Harbor Laboratory is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.Related content:
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