Making GeneChips™ at Affymetrix

A technician loads a quartz wafer into the DNA synthesizer, where nucleotides will be added to selected sequences to build probes.

quartz wafer,dna synthesizer,probes,sequences

  • ID: 15665
  • Source: DNALC.DNAi

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15666. Making GeneChips® at Affymetrix

The quartz wafer is in the holding position on the DNA synthesizer. The wafer is moved to a vertical reaction vessel for the process of DNA chain elongation.

  • ID: 15666
  • Source: DNALC.DNAi

15661. Making GeneChips™ at Affymetrix

Affymetrix, the makers of GeneChip™ arrays.

  • ID: 15661
  • Source: DNAi

15662. Making GeneChips™ at Affymetrix

Here you can see a technician shuttling a quartz wafer (containing 50-400 GeneChips™) between alternating photolithography and DNA synthesis steps.

  • ID: 15662
  • Source: DNAi

15664. Making GeneChips® at Affymetrix

A technician uses a computer guiding system to align the filter mask in perfect register with the quartz wafer. The filter mask will block light to selected regions of the wafer. More nucleotides can be added to the exposed regions.

  • ID: 15664
  • Source: DNALC.DNAi

15667. Making GeneChips® at Affymetrix

Here a technician aligns a quartz wafer, from which 50-400 GeneChips are prepared for mounting.

  • ID: 15667
  • Source: DNALC.DNAi

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Synthesizing human insulin using recombinant DNA, 3D animation with no audio

  • ID: 15505
  • Source: DNAi

15920. DNA arrays

In the 1990s, DNA arrays provided the means to analyze patterns of gene expression at different timepoints in a living cell.

  • ID: 15920
  • Source: DNAi

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Two sequencing techniques were developed independently in the 1970s. The method developed by Fred Sanger used chemically altered "dideoxy" bases to terminate newly synthesized DNA fragments at specific bases (either A, C, T, or G). These fragments are th

  • ID: 15922
  • Source: DNAi

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DNA profiling, DNA fingerprinting.

  • ID: 15583
  • Source: DNAi

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DNA fingerprints are also known as DNA profiles. They are now made using probes that detect differences in the number of short tandem repeats (STRs) between individuals.

  • ID: 15983
  • Source: DNAi