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ID 15703
BRCA1 cloned
Description:
In 1994, a group from Myriad and their collaborators announced that they located a strong candidate for BRCA1. Their patent on this gene was granted in 1997. Although they were not the first to find the second breast cancer gene (BRCA2), Myriad was the first to isolate it. They patented BRCA2 in 2001.
Keywords:
breast cancer gene,brca 1,breast cancer,collaborators,patent
This work by Cold Spring Harbor Laboratory is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.Related content:
- 15718. Mark Skolnick
- Mark Skolnick is Chief Scientific Officer at Myriad Genetics, Inc.
- SOURCE: DNAi
- 15938. What is breast cancer?
- BRCA1, on chromosome 17, is one of the genes associated with hereditary breast cancer.
- SOURCE: DNAi
- 15939. What is breast cancer?
- BRCA2, on chromosome 13, is one of the genes associated with hereditary breast cancer
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- 15702. BRCA1 and BRCA2 genes
- Tests are available to detect certain mutations in the BRCA1 and BRCA2 genes.
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- 15123. Testing for mutations in BRCA1, Mary-Claire King
- Mary-Claire King talks about testing for breast cancer.
- SOURCE: DNAi
- 15124. Better treatment for breast cancer, Mary-Claire King
- Mary-Claire King reflects on how knowledge gained from the identification of BRCA1 and BRCA2 could lead to improved cancer treatments.
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- 15408. Chromosome 13: BRCA2 gene for breast cancer susceptibility, Matt Ridley
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- 15126. Using pedigress in the hunt for BRCA1, Mary-Claire King
- Mary-Claire King talks about the value of using the centuries-old tool of family pedigrees to gain insight into patterns of inheritance of genetic disorders.
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- 15247. Onto BRCA2, Mark Skolnick
- Mark Skolnick talks about moving on after the discovery of BRCA1 to find and clone another gene associated with breast cancer, BRCA2.
- SOURCE: DNAi
- 15118. What to look for in the hunt for BRCA1, Mary-Claire King
- Mary-Claire King talks about her first steps toward finding the gene responsible for certain kinds of inherited breast cancer.
- SOURCE: DNAi
