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ID 15879

Semi-conservative replication

Description:
Matt Meselson and Frank Stahl's
Keywords:
dna replication,meselson,stahl
Creative Commons License This work by Cold Spring Harbor Laboratory is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.

Related content:

15880. Models of DNA replication
Three different models of DNA replication were proposed. Matt Meselson and Frank Stahl's experiment supported only one of the models.
15331. Proposed models of DNA replication, Matthew Meselson
Matt Meselson talks about the different models that were considered before their experiment.
16467. Biography 20: Franklin William Stahl (1929-)
Franklin Stahl and Matthew Meselson invented the technique of density gradient centrifugation and used this to prove that DNA is replicated semi-conservatively.
16466. Biography 20: Matthew Stanley Meselson (1930- )
Matthew Meselson and Franklin Stahl invented the technique of density gradient centrifugation and used this to prove that DNA is replicated semi-conservatively.
15329. How the second paper (on the replication of DNA) was written, Matthew Meselson
Matt Meselson talks about how he and Frank were "encouraged" by Max Delbruck to write up the results of their experiment on semi-conservative DNA replication.
15328. Meeting Frank Stahl, Matthew Meselson
Matt Meselson talks about how he met Frank Stahl, his partner in "the beautiful experiment." Together they proved that DNA is replicated semi-conservatively.
15332. Use of isotopes to determine correct DNA replication model, Matthew Meselson
Matt Meselson describes the experiment he did with Frank Stahl to prove that DNA is replicated semi-conservatively.
16469. Problem 20: A half DNA ladder is a template for copying the whole.
Explore other theories on DNA replication.
16450. Gallery 20: Matt Meselson and Frank Stahl, 1984
Matt Meselson and Frank Stahl in Oregon on a walk in the Cascade Mountains, 1984.
16462. Video 20: Matthew Meselson, clip 3
How Meselson came to read the Watson and Crick paper, then think about ways to experimentally test how DNA replicates.
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