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ID 15915

The first recombinant DNA

Description:
Stanley Cohen and Herbert Boyer's historic experiment used techniques to cut and paste DNA to create the first custom-made organism containing recombined or "recombinant" DNA.
Keywords:
dna recombination,herbert boyer,recombinant dna,stanley cohen,organism
Creative Commons License This work by Cold Spring Harbor Laboratory is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.

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15916. DNA transformation
Stanley Cohen and Herbert Boyer inserted the recombinant DNA molecule they created into E. coli bacteria by means of a plasmid, thereby inducing the uptake and expression of a foreign DNA sequence known as "transformation."
15074. Taking apart plasmid DNA, Stanley Cohen
Stanley Cohen speaks about his and Herbert Boyer's experiment to make the first plasmid that had been engineered to contain foreign DNA.
15646. Herbert Boyer
Image of Herbert Boyer. From lineman on the varsity football team to co-founder of the first biotech company, Boyer has never lacked imagination, drive, or vision. His and Stanley Cohen's recombinant DNA work paved the way for the biotech revolution.
15030. Implications of recombinant DNA work, Herbert Boyer
Herb Boyer reflects on the importance of their work on rDNA technology and its impact on understanding the genetics of higher organisms.
15028. Interest in plasmids, Herbert Boyer
Herb Boyer talks about Stanley Cohen's and his interest in plasmids as vectors for DNA.
16033. Stanley Cohen and Herbert Boyer, 1972
Genes can be moved between species.
15626. Paul Berg and Stanley Cohen
Herbert Boyer: Former varsity lineman turned biotech bigwig. Expert at cutting DNA before most people knew it could be done. Stanley Cohen: A born tinkerer; figured out the trick of using loops of DNA called plasmids to transform bacterial DNA
16721. Biography 34: Herb W. Boyer (1936 - )
Herb Boyer and Stan Cohen "invented" recombinant DNA technology.
16720. Biography 34: Stan Norman Cohen (1935 - )
Stan Cohen and Herb Boyer "invented" recombinant DNA technology.
16705. Animation 34: Genes can be moved between species.
Stanley Cohen and Herbert Boyer transform bacteria with a recombinant plasmid, and Doug Hanahan studies induced transformation.
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