BRCA1, on chromosome 17, is one of the genes associated with hereditary breast cancer. Although gender, age and environmental effects are major risk factors for breast cancer, having a mutation in either the BRCA1 gene or BRCA2 gene (on chromosome 13) increases the risk.
Keywords:
hereditary breast cancer,risk factors for breast cancer,brca1 gene,chromosome 13,breast cancer,gender age,mutation,genes
Mary-Claire King talks about the value of using the centuries-old tool of family pedigrees to gain insight into patterns of inheritance of genetic disorders.
Mary-Claire King speaks about how much was yet to be understood about the genetic mechanisms of cancer when she began her hunt for genes associated with breast cancer.