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ID 15968

What causes sickle cell?

Description:
Mutations in the HBB gene on chromosome 11 can cause sickle cell. The beta globin protein is one of the subunits of hemoglobin, a protein necessary for the oxygen-carrying function of red blood cells. People with the sickle cell mutation in both copies of the HBB gene produce proteins that clump together and lead to changes in the shape and behavior of red blood cells.
Keywords:
red blood cells,function of red blood cells,sickle cell mutation,chromosome 11,clump,hemoglobin,subunits,mutations,proteins,oxygen,protein,shape,beta globin
Creative Commons License This work by Cold Spring Harbor Laboratory is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.

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