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Genetic and physical mapping

Interviewee: David Botstein<br><br> DNAi Location:<br>Genome>The Project>players>public<br><br> Genetic and physical mapping David Botstein, a prominent Stanford geneticist, talks about his initial involvement in Human Genome Project discussions and the value of genome maps.
I was invited largely because I had been involved in gene mapping, because a few years before in 1980 three colleagues and I had published a proposal for making a genetic map of the human genome with DNA markers that could be useful for finding disease genes. And by the time of the Santa Cruz meeting it was clear not only that you could find disease genes this way, but that it would really be useful to have more infrastructure, mainly a genetic and physical map that would greatly speed up this process.
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