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ID 16950
2D Animation of Antisense Oligonucleotide Therapy for SMA
Description:
An animation shows how antisense oligonucleotide therapy for SMA changes the way the SMN2 gene is spliced.
Keywords:
Spinal muscular atrophy, SMA, RNA, mRNA, splicing, gene, genetic, DNA, antisense, motor neuron, splice, Therapy, Alternative splicing, SMN2, exon, intron, transcript, restore, express, gene expression, promoter, suppressor, enhancer, silencer, oligonucleotide, antisense, inclusion, axon, exon 7
This work by Cold Spring Harbor Laboratory is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.Related content:
- 16948. Alternative RNA Splicing Therapy for Spinal Muscular Atrophy
- Drs. Sharp and Sumner describe how RNA splicing can be used as a therapy for SMA.
- SOURCE: DNALC.SMA
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- Dr. Krainer explains the science behind antisense therapy for SMA.
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- 16941. 2D Animation of Alternative RNA Splicing
- An animation shows alternate splicing of the SMN2 gene.
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- 16938. 3D Animation of RNA Splicing
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- 16935. The Connection Between SMA and RNA Splicing
- Dr. Krainer explains the connection between SMA and RNA splicing.
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- 16939. RNA Splicing
- A step-by-step 2D animation shows the details of RNA splicing.
- SOURCE: DNALC.SMA
- 16929. Genes Involved with SMA
- Dr. Sumner explains how SMA is related to changes in the SMN1 and SMN2 genes.
- SOURCE: DNALC.SMA
- 16940. Alternative RNA Splicing
- Drs. Sharp and Krainer explain how genes can be alternatively spliced.
- SOURCE: DNALC.SMA
- 16937. An Explanation of RNA Splicing
- Dr. Sharp explains the process of RNA splicing.
- SOURCE: DNALC.SMA
- 16933. 3D Animation of DNA to RNA to Protein
- An animation shows how the DNA genetic “code” is made into protein.
- SOURCE: DNALC.SMA
