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ID 1717

Rat (Rattus norvegicus)

Description:
The rat is an ideal research model because scientists have a deep understanding of rat physiological mechanisms. There are numerous rat models that mimic human diseases.
Transcript:
The rat is used extensively as a model organism for studying both normal and disease processes in the human. The rat is an ideal research model because scientists have a deep understanding of rat physiological mechanisms. There are numerous rat models that mimic human diseases. It is relatively easy to generate inbred congenic (nearly identical) and consomic strains. A consomic strain is an inbred strain with one of its chromosomes replaced by the homologous chromosome of another inbred strain via a series of marker-assisted backcrosses.
Keywords:
Rat, rattus norvegicus, model, systems, organisms, homology
Creative Commons License This work by Cold Spring Harbor Laboratory is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.

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