The fruit fly is easy to maintain, has large numbers of offspring, and grows quickly. The fruit fly shares with humans a number of so-called “master,” or homeotic, genes.
Transcript:
The fruit fly is a small invertebrate. Although it cannot be frozen like bacteria and worms, it is easy to maintain, has large numbers of offspring, and grows quickly – from embryo to adult in 12 days. The fruit fly shares with humans a number of so-called “master,” or homeotic, genes that control development of a complex, symmetrical body plan. Thomas Hunt Morgan and his students at Columbia University identified the first fruit fly mutations in the early 1900s. Since that time, scientists have developed a large library of genetic mutants. It is relatively straightforward to disrupt fruit fly genes and to introduce foreign ones. All of these features make Drosophila a powerful model organism for studying animal development and even elements of behavior – including learning and memory!
Keywords:
fruit fly, drosophila melanogaster, model, systems, organisms, homeotic genes, thomas hunt morgan, mutations
Thomas Hunt Morgan established the chromosomal theory of inheritance. He used fruit flies with eye color mutations to demonstrate sex-linked inheritance patterns.
Doctor Josh Dubnau explains that model systems are particular species of animals that substitute for humans or other animals. For genetic and historic reasons, the fruit fly is a commonly used model.
Model organisms such as yeast, bacteria, the mouse and the fruit fly are used by researchers to study biological systems. The genomes of these organisms have been mapped and sequenced.
Calvin Bridges was a student of Thomas Hunt Morgan. Bridges advanced the theory of chromosomal non-disjunction, and did a lot of work on chromosomal banding patterns.