Professor Allen Moore explains that since the beginning of the human genome project sequencing technology has become considerably cheaper and we now have sequences for many different organisms.
Transcript:
Well the technologies are really the main thing that’s changed in the last 10 years. It started out that you would sequence DNA by hand – going through very carefully and figuring out which different sequences were, and then you could do it by machine and eventually the machines get faster and faster and at this point now you can sequence entire genomes in a very short period of time for a lot less money. So the human genome project, one of the outcomes of that project, was that sequencing became much faster, much cheaper, and now we can have sequences for a lot of different organisms.
Keywords:
sequence dna, sequencing, technology, human genome project, allen moore
Professor Allen Moore explains that the DNA code is a long sequence made up of four bases (A,C,T, and G) and DNA sequencing is the processes of identifying the order in which they occur.
Prof. Allen Moore explains that bioinformatics can deal with a huge amount of genomic data, allowing researchers to explore complex relationships between many genes or genomes.
Professor Allen Moore describes the differences between linkage and association studies, which are low- and high-resolution techniques used to search for candidate genes.
Professor Allen Moore outlines the differences between quantitative genetics and linkage studies. With quantitative genetics it is not necessary to begin with the physical DNA.
Ari Patrinos, director of the US Department of Energy's sequencing effort, talks about the public genome project's aims that extended beyond those of the private project.