Professor James Eberwine describes the primary functions of RNA-binding proteins, which include regulating tRNAs, degrading RNAs, synthesizing RNAs, and regulating multigenic gene expression.
Transcript:
RNA-binding proteins are proteins that are existent within the cell that bind RNA. These can occur in the nucleus, cytoplasm, or even subcellular regions in the neurons, dendrites, and potentially axons. RNA-binding proteins regulate the translation of RNAs, the degradation of RNAs, and the synthesis of RNAs and they're important regulators of multigenic gene expression.
Professor James Eberwine describes three ways in which experiences can change the gene-expression: changing RNA translation, movement, and potentially production.
Professor James Eberwine discusses the structural changes in a cell related to long-term potentiation. These include changes in the shape of dendritic spines.
Doctor Josh Dubnau explains that some genes are preferentially active in one part of the brain or body, while other genes are particular active in another location.
In this section learn that in the cytoplasm, the messenger RNA is released from its carrier proteins and binds to a protein assembly complex called a ribosome.
Professor James Eberwine discusses what we might see were we to take a snapshot of the internal dynamics of a living cell, which might resemble Grand Central Station during rush hour.