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ID 2336
Neurofibrillary Tangles - Hallmark of Alzheimer's Disease
Description:
Doctor Brian Bacskai discusses what a tangle is and how it leads to death of neurons.
Transcript:
Neurofibrillary tangles are the other classic histopathological hallmark of Alzheimer’s disease. [They] are an intracellular lesion based on aberrant phosphorylation of the Tau protein that lead to sort of an accumulation of Tau, known as a tangle, inside the cell, ultimately leading to death of those neurons.
Keywords:
neurofibrillary, tangle, tau, protein, hallmark, alzheimer, brian, bacskai
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This work by Cold Spring Harbor Laboratory is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.Related content:
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