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Whole Genome Association

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553. Whole Genome Association
Special techniques are used for screening each individual’s genome for millions of different SNPs. This kind of comparison is referred to as a genome-wide association study.
2300. Studies of Genes in Bipolar Disorder and Schizophrenia
Doctor Anil Malhotra discusses the search for genes in both bipolar disorder and schizophrenia, both of which are in their infancy.
2312. Microarray Studies - Assessing Statistical Significance
Doctor Anil Malhotra discusses the problem of deciding what meets the criteria for statistical significance for microarray studies.
2311. Microarray Studies - Danger of False Positives
Doctor Anil Malhotra discusses that because whole genome microarray studies examine so much genetic data, the daners of false-positive results are very real.
1178. What is a Microarray?
Professor Daniel Geschwind describes microarrays, small slides onto which DNA can be pasted, as an efficient way to study genes that cause disorders.
2020. Linkage versus association studies
Professor Allen Moore describes the differences between linkage and association studies, which are low- and high-resolution techniques used to search for candidate genes.
16884. Genome Scans Pay Off
Scans of the entire human genome turn up genes involved in common diseases.
1979. Linkage and association studies
Professor James Potash describes the difference between linkage and association studies, which are two ways of locating candidate genes. These are discussed in reference to bipolar disorder,
2018. Bioinformatics defined
Prof. Allen Moore explains that bioinformatics can deal with a huge amount of genomic data, allowing researchers to explore complex relationships between many genes or genomes.
2017. Linkage studies versus quantitative genetics
Professor Allen Moore outlines the differences between quantitative genetics and linkage studies. With quantitative genetics it is not necessary to begin with the physical DNA.
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