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ID 793
Whole Genome Association
This work by Cold Spring Harbor Laboratory is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.Related content:
- 553. Whole Genome Association
- Special techniques are used for screening each individual’s genome for millions of different SNPs. This kind of comparison is referred to as a genome-wide association study.
- SOURCE: G2C
- 2300. Studies of Genes in Bipolar Disorder and Schizophrenia
- Doctor Anil Malhotra discusses the search for genes in both bipolar disorder and schizophrenia, both of which are in their infancy.
- SOURCE: G2C
- 2312. Microarray Studies - Assessing Statistical Significance
- Doctor Anil Malhotra discusses the problem of deciding what meets the criteria for statistical significance for microarray studies.
- SOURCE: G2C
- 2311. Microarray Studies - Danger of False Positives
- Doctor Anil Malhotra discusses that because whole genome microarray studies examine so much genetic data, the daners of false-positive results are very real.
- SOURCE: G2C
- 1178. What is a Microarray?
- Professor Daniel Geschwind describes microarrays, small slides onto which DNA can be pasted, as an efficient way to study genes that cause disorders.
- SOURCE: G2C
- 2020. Linkage versus association studies
- Professor Allen Moore describes the differences between linkage and association studies, which are low- and high-resolution techniques used to search for candidate genes.
- SOURCE: G2C
- 16884. Genome Scans Pay Off
- Scans of the entire human genome turn up genes involved in common diseases.
- SOURCE: DNALC
- 1979. Linkage and association studies
- Professor James Potash describes the difference between linkage and association studies, which are two ways of locating candidate genes. These are discussed in reference to bipolar disorder,
- SOURCE: G2C
- 2018. Bioinformatics defined
- Prof. Allen Moore explains that bioinformatics can deal with a huge amount of genomic data, allowing researchers to explore complex relationships between many genes or genomes.
- SOURCE: G2C
- 2017. Linkage studies versus quantitative genetics
- Professor Allen Moore outlines the differences between quantitative genetics and linkage studies. With quantitative genetics it is not necessary to begin with the physical DNA.
- SOURCE: G2C
