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ID 919
SHANK3 Gene
Description:
The SHANK3 gene is associated with a number of cognitive disorders including autism.
Transcript:
The SHANK3 (SH3 and multiple ankyrin repeat domains 3) gene spans 60 kb and contains 22 exons. SHANK3 is associated with a number of severe cognitive deficits, including language and speech disorders, mental retardation, and autism. SHANK3 proteins interact with neuroligins, cell surface proteins that binds to synaptic membranes and facilitate neurotransmission.
Keywords:
SHANK3, gene, autism, autistic, mental, retardation, language, speech, neurotransmission, neuroligin
This work by Cold Spring Harbor Laboratory is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.Related content:
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