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Hallmarks, Evading death: Hanahan

Description:
Professor Douglas Hanahan explains that a fundamental property of multi-cellular organisms is the capability to have cells commit suicide or undergo apoptosis, which is a form of programmed cell death.
Transcript:
In 2000, Douglas Hanahan (shown below) and Robert Weinberg published a paper in Cell, "The Hallmarks of Cancer," which identified some organizing principles of cancer cell development. “A fundamental property of multi-cellular organisms is the capability to commit suicide or undergo apoptosis, which is a form of programmed cell death. And it is evident that this is another check and balance on aberrant tissues, so that early on in the development of many cancers one can see prominent induction of apoptosis, which we imagine to be a form of protection for the organism. The cells are proliferating aberrantly and they therefore commit suicide for the common good.”
Keywords:
programmed cell death, fundamental property, cancer cell, professor douglas, apoptosis, hallmarks, organisms, organism, cancers, induction, tissues
Creative Commons License This work by Cold Spring Harbor Laboratory is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.

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