Website Search
ID 1208

Long-term Potentiation

Professor Seth Grant explains that long-term potentiation is based on the principle that synapses become stronger with experience.
Long-term potentiation and long-term depression of synaptic transmission is a highly studied area of neurobiology. It is studied because it is thought, although not proven, to be a memory mechanism. Simply put, if synapses become stronger with experience, then it seems logical that that might be a way of storing memories.
long, term, potentiation, depression, memory, neurobiology, synapse, seth, grant
Creative Commons License This work by Cold Spring Harbor Laboratory is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.

Related content:

1210. Long-term Potentiation and Learning
Professor Seth Grant discusses the complicated relationship between long-term potentiation and learning/memory.
1217. Long- and Short-term Memory Differences (2)
Professor Seth Grant explains that long-term memories are created when the synapse sends a signal to the nucleus to activate certain genes.
1209. How Long is LTP?
Professor Seth Grant explains that long-term potentiation may last for days or weeks, but is usually studied over the course of several hours.
550. The Neural Code
Cognitive information is encoded in patterns of nervous activity and decoded by molecular listening devices at the synapse. Professor Seth Grant explains how different patterns of neural firing are critical to cognition.
2037. Synapse changes during learning
Professor Kenneth Kosik discusses changes in synapses that accompany long-term potentiation, which include enlarged dendritic spines.
1212. NMDA Receptors and Learning (1)
Professor Seth Grant explains that NMDA receptors are important to forming memories - if we block NMDA receptors, we can block learning.
1107. Depotentiation
Professor Tom O'Dell defines depotentiation - the erasure of long-term potentiation (LTP) at the synapse.
1108. Synaptic Plasticity (1)
Professor Tom O'Dell discusses synaptic plasticity - the strengthening and weakening of synaptic connections between neurons.
1098. Long-term Potentiation
Professor Graham Collingridge describes the process of long-term potentiation (LTP) - the process by which synapses increase their efficiency.
549. Long-term Potentiation
Long-term Potentiation of synaptic transmission is commonly referred to as LTP. It can be recorded in many parts of the nervous system, but is very widely studied in the hippocampus.
Cold Spring Harbor Laboratory
CSHL HomeAbout CSHLResearchEducationPublic EventsNewsstandPartner With UsGiving