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ID 1254

Schizophrenia - Motor Control

Description:
Professor David Lewis explains that schizophrenic individuals can have coordination problems, which may relate to impaired neural circuits.
Transcript:
In addition to the symptoms that we recognize clinically as schizophrenia, individuals with that disorder can also have problems with motor control. They have difficulties with moving their eyes to follow a moving object and in the actual initial recognition of the illness by Kraepelin, he described kind of an awkward clumsy behavior. So, while this is a well recognized disturbance in the illness, it is less well understood what actually are the underlying disturbances in the neural circuitry that give rise to these motor abnormalities. I think one of the open questions in schizophrenia now is, is there a conserved disturbance in neural circuitry that, by virtue of affecting different regions of the brain, can give rise to different symptoms of the disorder: the psychotic symptoms, the negative symptoms, or the impairments in cognition, and, perhaps as well, the disturbances in motor performance?
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