Interviewee: Mark Skolnick. Using RFLPs or SNPs to study patterns in families.

When people refer to restriction fragment length polymorphisms, also known as RFLPs, or SNPs, single nucleotide polymorphisms, these are just different techniques for measuring DNA variation, which all of us have in the very long three billion base DNA sequence. So there are the DNA bases that make up the genetic code, the genes that cause the proteins. And variations both within the genes and between the genes, can be used to follow patterns in families.

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