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ID 15272

The molecular biology of the lac operon, Fraois Jacob

Description:
Interviewee: François Jacob. François Jacob talks about the relationship between DNA, ribosomes, and protein production. (DNAi Location: Code > Copying the code > Players > François Jacob > What drives protein production?)
Transcript:
The idea was that when you had the gene galactosidase, the enzyme synthesis starts immediately. Now if we were right and if there was no stable ribosome, if you can remove the gene then it should stop. And we could remove the gene because we had done in Paris an experiment where we loaded the donor chromosome with P32, radioactive P32, then let it go into the recipient, then put it in the cold and let it decay and see whether once the chromosome has been decaying it still makes enzyme on there, and the answer was no. That is as soon as the gene is destroyed by P32 decay, then the capacity to produce the enzyme is stopped.
Keywords:
lac operon,jacques monod,franis,protein production,dnai,molecular biology,location code,galactose,ribosomes,ribosome,interviewee,chromosome,glucose,jacob,dna,synthesis,recipient,relationship,paris
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Creative Commons License This work by Cold Spring Harbor Laboratory is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.

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