Website Search

Flash Player may be required. Please install and enable Flash.

ID 15418

Mitochondrial DNA, Matt Ridley

Interviewee: Matt Ridley. Every human cell has a "second" genome, found in the cell's energy-generating organelle, the mitochondrion. Comparison of control region sequences of mt DNA reveals that most people have a unique pattern of single nucleotide polymorphisms (SNPs). These sequence differences, in turn, are the basis for far-ranging investigations on human DNA diversity and the evolution of hominids. (DNAi Location: Genome > Tour > Genome spots > mt: Genealogy)
There's one set of human genes that's not found in the nucleus. It's in the mitochondrion. The mitochondrion is a sort of power pack inside the cell."+" Mitochondrial genes are passed through the mother's line, so I would get mine from my mother, and my son would get his from my wife. Because they don't mix with genes from the father's line, mitochondrial genes can be used to trace a sort of lineage right the way back to when our first ancestors came out of Africa.
evolution of hominids,single nucleotide polymorphisms,mitochondrial dna,matt ridley,maternal lineage,mitochondrial genes,human genes,human dna,sequence differences,dnai,s line,interviewee,mitochondrion,nucleus,ancestors,sequences,investigations,diversity,africa
Creative Commons License This work by Cold Spring Harbor Laboratory is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.

Related content:

15165. Mitochondrial Eve, Mark Stoneking
Geneticist Mark Stoneking, one of the authors of a controversial 1987 paper on mtDNA, talks about our common female ancestor.
15183. Support from Mitochondrial DNA, Douglas Wallace
Mitochondrial DNA research pioneer Douglas Wallace speaks about mitochondrial DNA and theories of human evolution.
15978. Mitochondrial DNA: a closer look
DNA found in the mitochondrion of a cell differs in structure and is separate from the DNA found in the cell nucleus. Mitochondrial DNA, or mtDNA, exists as a circular loop of double-stranded DNA rather than the linear form found in nuclear DNA. However,
15178. Mitochondrial DNA and the molecular clock, Douglas Wallace
Geneticist Douglas Wallace explains a method of mapping a population's history using the mutations accumulated by its members.
15610. Mitochondrial DNA (mtDNA) human family tree
This illustration shows the two major mitochondrial DNA lineages. The lower branch includes only African populations. The upper branch has both African and non-African members.
15979. A mitochondrial DNA sequence
Human mitochondrial DNA is 16,569 base pairs in length.
15186. From Africa to Europe and Asia s, Douglas Wallace
Mitochondrial DNA pioneer Douglas Wallace explains the movement of different lineages of humans from Africa into Europe and Asia.
15154. Analyzing Neandertal DNA, Svante Paabo
Evolutionary geneticist Svante Paabo talks about his team's pioneering work with ancient Neandertal mtDNA.
15166. Constructing our family tree, Mark Stoneking
Geneticist Mark Stoneking speaks about the findings of early mitochondrial DNA studies.
16611. Problem 27: Mutations are changes in genetic information.
Use mutations to measure human evolution.
Cold Spring Harbor Laboratory
CSHL HomeAbout CSHLResearchEducationPublic EventsNewsstandPartner With UsGiving