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ID 15691

Walter Gilbert (1987)

Child prodigy and yet another physics convert, Gilbert was a Harvard physics professor who found himself spending more and more time in biology laboratories. His switch to biology helped foster a new generation of scientists.
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Creative Commons License This work by Cold Spring Harbor Laboratory is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.

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16697. Video 33: Walter Gilbert, clip 4
How Jacob and Monod showed the existence of the inhibitor (what Gilbert calls the repressor).
16698. Video 33: Walter Gilbert, clip 5
Jacob and Monod never identified the inhibitor, but Gilbert found it.
16549. Biography 24: Phillip Allen Sharp (1944- )
Phil Sharp and Richard Roberts shared the 1993 Nobel Prize for the discovery of the split gene theory.
16694. Video 33: Walter Gilbert, clip 1
Before Jacob and Monod, people thought the amount of protein in a cell was constant and proteins turned themselves off.
16695. Video 33: Walter Gilbert, clip 2
Jacob and Monod discovered that genes control the amount of protein in a cell.
16696. Video 33: Walter Gilbert, clip 3
Where did the idea of negative control come from?
16699. Video 33: Walter Gilbert, clip 6
What we know about gene regulation today.
16700. Video 33: Walter Gilbert, clip 7
To explain their data, Jacob and Monod had to hypothesize the existence of mRNA.
16807. Biography 38: Howard Robert Horvitz (1947 - )
Bob Horvitz and Mike Hengartner used C. elegans to work out the mechanism of programmed cell death.
16722. Biography 34: Doug Hanahan (1951 - )
Doug Hanahan refined transformation methods for DNA uptake into bacteria.
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