Website Search
ID 15903

Neurofibromatosis 1

Description:
NF1 is a large gene that encodes three slightly different neurofibromin proteins, found in nerve and muscle tissues. These proteins act as part of a cell's signalling pathway and help to regulate cell growth and repair. Mutations in the NF1 gene can disrupt the function or production of neurofibromin proteins, leading to tumor growth in bones and the peripheral nervous system.
Keywords:
nf1 gene,muscle tissues,peripheral nervous system,nerve and muscle,tumor growth,proteins,mutations,pathway,bones
Creative Commons License This work by Cold Spring Harbor Laboratory is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.

Related content:

15959. What is Neurofibromatosis 1?
NF1 is a large gene that encodes three slightly different neurofibromin proteins, found in nerve and muscle tissue
15960. What causes Neurofibromatosis 1?
NF1 is a large gene that encodes three slightly different neurofibromin proteins, found in nerve and muscle tissues.
15904. Neurofibromatosis 2
The NF2 gene produces a protein, called merlin, in the schwann cells that wrap around the axons of nerve cells.
15962. What causes neurofibromatosis 2?
The NF2 gene produces a protein, called merlin, in the schwann cells that wrap around the axons of nerve cells. Merlin is a tumor suppressor protein, involved in regulation of the cell's activities. If the merlin protein is mutated, the schwann cells can
1904. A0443
The A0443 protein is a calcium-binding aspartate/glutamate carrier of the mitochondrial inner membrane.
15961. What is neurofibromatosis 2?
The NF2 gene produces a protein, called merlin, in the schwann cells that wrap around the axons of nerve cells.
1794. NF1/A0196
Neurofibromin 1, also known as NF1 or A0196, is a multifunctional protein, which acts as an inhibitory element on Ras signaling.
1018. Pathways, At the cell surface
In this section learn that a signaling pathway begins with the arrival of a chemical signal – such as a hormone or growth factor – at the cell surface.
868. Candidate Genes for Schizophrenia
An interactive chromosome map of the genes and loci associated with schizophrenia.
1893. Myosin V/A0149
Myosin V, also known as A0149, is a processive, non-muscle actin-based motor protein that undergoes multiple catalytic cycles and can move in large steps through the actin filament.
Cold Spring Harbor Laboratory
CSHL HomeAbout CSHLResearchEducationPublic EventsNewsstandPartner With UsGiving