Website Search
ID 510

GRM3 Gene

Description:
Metabotropic Glutamate Receptor-3 (GRM3) is a candidate gene for schizophrenia.
Transcript:
Metabotropic Glutamate Receptor-3 (GRM3) is a G-protein coupled receptor for glutamate, a major excitatory neurotransmitter. GRM3 also modulates serotonin and dopamine transmission. Several association studies have linked GRM3 polymorphisms to schizophrenia, suggesting functional changes in glutamate transmission in the prefrontal cortex and hippocampus.
Keywords:
schizophrenia, gene, candidate, GRM3, grm, metabotropic, glutamate, Receptor-3, g protein coupled receptor, g protein, dopamine, cyclic amp, c-amp, camp, guanine, polymorphisms, gtp
Creative Commons License This work by Cold Spring Harbor Laboratory is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.

Related content:

868. Candidate Genes for Schizophrenia
An interactive chromosome map of the genes and loci associated with schizophrenia.
511. RGS4 Gene
Regulator of G-Protein Signaling 4 (RGS4) is a candidate gene for schizophrenia.
1365. CREB1 Gene
The cAMP response element-binding protein 1 (CREB1) gene is a CREB activator and has been found to facilitate long-term memory formation.
1366. CREB2 Gene
CAMP response element-binding protein 2(CREB2) is also known as Activating Transcription Factor 2 (ATF2). CREB2 is a CREB repressor, which means it inhibits long-term memory formation.
1735. GRIN1A/A0002
Grin2a (glutamate receptor, ionotropic, NMDA2A (epsilon 1)) also known as NR2A, is a type of NR2 subunit of the transmembrane N-methyl-D-aspartate (NMDA) receptor.
1733. GRM/A0327
GRM1, also known as A0327, is a non-ionotropic G-coupled protein glutamate receptor.
1732. mGluR1/A0103
The metabotropic glutamate receptor 1 (mGluR1, also known as GRM1 or A0103), is a non-ionotropic G-coupled protein glutamate receptor.
1390. Genes for Learning and Memory
An interactive chromosome map of the genes and loci associated with learning and memory.
509. PPP1R1B Gene
Protein Phosphatase 1, Regulatory Subunit 1B (PPP1R1B) is a candidate gene for schizophrenia.
1431. CAMP Signaling Network
Doctor Josh Dubnau explains that the cyclic AMP (cAMP) signaling network can receive signals from outside the cell and use the signal to alter the function of the cell.
Cold Spring Harbor Laboratory
CSHL HomeAbout CSHLResearchEducationPublic EventsNewsstandPartner With UsGiving