Website Search
ID 963

Causes, Smoking: Prevention, Dennis

Professor Dennis explains that the implications of smoking cessation are profound and this is the most readily identifiable cause of lung cancer and is clearly something where one can intervene.
Phillip Dennis, M.D., Ph.D. is head of the Signal Transduction section medical oncology at the National Naval Medical Center. He is interested in how components of tobacco smoke activate signaling pathways that allow cancer cells to evade programmed cell death (apoptosis). β€œThe implications of smoking cessation are profound. This is the most readily identifiable cause of lung cancer and is clearly something where we can intervene. In fact, in the state of California, they have been successful in decreasing the prevalence of smoking from 24% – which is on the national average – to about 12%. Aggressive anti-smoking campaigns that are comprehensive in their approach can do more to decrease the rate of lung cancer than any other intervention.”
anti smoking campaigns, cause of lung cancer, cancer cells, signaling pathways, national naval medical center, smoking cessation, medical oncology, naval medical center, smoking smoke, tobacco smoke, lung cancer, cell death, signal transduction, state of california, prevalence, oncology, prevention
Creative Commons License This work by Cold Spring Harbor Laboratory is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.

Related content:

962. Causes, Smoking: Prevention
In this section learn about the interventions and research being carried out to control cancer.
954. Causes, Smoking, all sections
This section explains that lung cancer is the leading cause of cancer deaths in the United States and it is almost entirely preventable, since the vast majority of cases are due to cigarette smoking.
956. Causes, Smoking: Lung cancer epidemic
This section covers the smoking epidemic in the U.S. and the 163,000 Americans that die each year from lung cancer, which is greater than deaths caused by prostate, breast, colon, and pancrease cancers combined.
961. Causes, Smoking: Nicotine connection
Nicotine has long been known to be the habit-forming drug in cigareette smoke, but recent research shows that nicotine also works with other components of smoke to promote cancer formation.
964. Causes, Smoking: Prevention, Sorenson clip 1
Professor Sorenson explains that tobacco use in the population overall is probably around 20-21% right now in terms of prevalence.
957. Causes, Smoking: Killers in smoke
In this section the suspected cancer-causing agents (carcinogens) - including polyaromatic hydrocarbons (PAHs), nitrosamines, and heavy metals found in cigarettes will be introduced.
966. Causes, Smoking: Prevention, Sorenson clip 3
Profesor Sorenson explains how studies were carried out to aid blue collar workers towards quitting smoking.
967. Causes, Smoking: Prevention, Sorenson clip 4
Professor Sorenson explains how surveys were conducted to elucidate how diferent programs elicite a varied response amongst blue collar workers to quit smoking.
965. Causes, Smoking: Prevention, Sorenson clip 2
Professor Sorenson explains that some of the large public service campaigns or public information campaigns that have occurred over the last decade have clearly influenced more educated sectors of the population to make changes in reducing tobacco use.
960. Causes, Smoking: p53
This series of animations shows how mutations in the p53 gene are found in 70% of lung tumors, the highest rate for any cancer.
Cold Spring Harbor Laboratory
CSHL HomeAbout CSHLResearchEducationPublic EventsNewsstandPartner With UsGiving