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ID 983

Causes, Diet: Cause, Nelson

Description:
Professor Nelson explains that GSTP1 doesn't seem to be a gene in prostate cancer at least that's controlling growth, invasion, or metastasis.
Transcript:
William Nelson, M.D., Ph.D. is a researcher at the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins. HIs research focuses on the molecular causes involved in the development of prostate cancer. This has led to the discoveries that inflammation, diet, and gene "silencing" have roles in prostate cancer development. “GSTP1 doesn't seem to be a gene in prostate cancer at least that's controlling growth, invasion, or metastasis or something that you might imagine a classical tumor suppressor gene to do. Rather, it seems to be a gene that controls the vulnerability to further gene damage by reactive oxygen species and carcinogens. So in that sense it acts more like a repair enzyme that is protecting the genome against damage.”
Keywords:
sidney kimmel comprehensive cancer center, sidney kimmel comprehensive cancer center at johns hopkins, tumor suppressor gene, gene damage, oxygen species, cancer development, professor nelson, sidney kimmel comprehensive, william nelson, prostate cancer, inflammation diet, metastasis, vulnerability, invasion
Creative Commons License This work by Cold Spring Harbor Laboratory is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.

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