Website Search
ID 15242
Using RFLPs or SNPs to study patterns in families, Mark Skolnick
Description:
Interviewee: Mark Skolnick.
Using RFLPs or SNPs to study patterns in families.
Transcript:
When people refer to restriction fragment length polymorphisms, also known as RFLPs, or SNPs, single nucleotide polymorphisms, these are just different techniques for measuring DNA variation, which all of us have in the very long three billion base DNA sequence. So there are the DNA bases that make up the genetic code, the genes that cause the proteins. And variations both within the genes and between the genes, can be used to follow patterns in families.
Keywords:
restriction fragment length,fragment length polymorphisms,restriction fragment length polymorphisms,dna variation,nucleotide polymorphisms,rflps,dna sequence,snps,genetic code,interviewee,genes,proteins,variations
Downloads:
This work by Cold Spring Harbor Laboratory is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.Related content:
- 554. Single Nucleotide Polymorphisms
- A single nucleotide polymorphism, or SNP, occurs when two individuals in the population differ by a single letter in the DNA sequence.
- SOURCE: G2C
- 16832. Problem 39: A genome is an entire set of genes.
- Locate a disease gene by screening for markers linked to the gene.
- SOURCE: DNAFTB
- 16529. Animation 24: The RNA message is sometimes edited.
- Rich Roberts and Phil Sharp explain restriction enzymes, electrophoresis, and split genes.
- SOURCE: DNAFTB
- 15557. Single nucleotide polymorphisms (SNPs)
- An image of a family tree depicting the occurance of single nucleotide polymorphisms.
- SOURCE: DNAi
- 552. Copy Number Variants
- Humans differ not only at the level of DNA sequence. It has been recently discovered that humans can also differ in the number of copies of each gene. These are called copy number variants.
- SOURCE: G2C
- 15092. Studying the Y chromosome to understand population origins and migration, Michael Hammer
- Evolutionary geneticist Michael Hammer speaks about the markers used to analyze DNA variation in the Y chromosome.
- SOURCE: DNAi
- 15917. Cutting and pasting DNA
- The discovery of enzymes that could cut and paste DNA made genetic engineering possible.
- SOURCE: DNAi
- 15116. Frequency of different DNA variations, Kenneth Kidd
- Kenneth Kidd talks about frequency of different DNA variations.
- SOURCE: DNAi
- 2309. Genotyping with Microarray Technologies
- Doctor Anil Malhotra discusses new technologies that allow scientists to genotype large numbers of genetic polymorphisms.
- SOURCE: G2C
- 15632. Chromosome 11: Intergenic region repeats and transposons, 3D animation
- Take a guided tour of less than 1% of your genetic material to see new and unusual views of your chromosomal landscape.
- SOURCE: DNAi
