Website Search
ID 15416

Chromosome 21: trisomy and Down Syndrome, Matt Ridley

Description:
Interviewee: Matt Ridley. People with Down Syndrome (DS) have an excess of genetic material in their cells. The vast majority of people with this syndrome have an extra copy of chromosome 21. Down syndrome is one of the most commonly occurring genetic birth defects, and it is the most common genetic basis for mental retardation. (DNAi Location: Genome >Tour > Genome spots > Chromosome 21: Down syndrome > A Chromosome 21)
Transcript:
Chromosome 21 is one of the smallest chromosomes. Some people are born with three copies of chromosome 21 instead of two. You might think this wouldn't matter, but it unbalances the development of the embryo, and the result is Down Syndrome. Down Syndrome is commonest in women bearing children later in life. It's one of the commonest genetic prenatal tests available to women who have a concern over this problem.
Keywords:
genetic birth defects,chromosome 21,matt ridley,development of the embryo,prenatal tests,dnai,extra copy,trisomy,genetic basis,interviewee,genetic material,chromosomes,mental retardation,birth defects,cells
Downloads:
Creative Commons License This work by Cold Spring Harbor Laboratory is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.

Related content:

15943. What is Down syndrome?
People with Down Syndrome (DS) have an excess of genetic material in their cells.
15944. What causes Down syndrome?
People with Down Syndrome (DS) have an excess of genetic material in their cells.
15897. Down syndrome
People with Down Syndrome (DS) have an excess of genetic material in their cells. The vast majority of people with this syndrome have an extra copy of chromosome 21. Down syndrome is one of the most commonly occurring genetic birth defects, and it is the
865. Mental Retardation
Mental retardation: struggle, stigma, science.
15414. Chromosome 19: APOE gene and susceptibility to Alzheimer's, Matt Ridley
Matt Ridley talks about chromosome 19, APOE gene and susceptibility to Alzheimer's.
15403. Chromosome 8: transposable elements, Matt Ridley
Matt Ridley talks about chromosome 8, transposable elements.
15410. Chromosome 15: Prader-Willi's disease, or Angelman's syndrome, Matt Ridley
Matt Ridley talks about chromosome 15, Prader-Willi's disease, or Angelman's syndrome
15399. Chromosome 4: Huntington's Disease, Matt Ridley
Matt Ridley talks about chromosome 4, Huntington's Disease.
15397. Chromosome 2: fusion of 2 small chromosomes, Matt Ridley
Matt Ridley talks about chromosome 2, fusion of 2 small chromosomes.
15408. Chromosome 13: BRCA2 gene for breast cancer susceptibility, Matt Ridley
Matt Ridley talks about chromosome 13, BRCA2 gene for breast cancer susceptibility.
Cold Spring Harbor Laboratory
CSHL HomeAbout CSHLResearchEducationNews & FeaturesCampus & Public EventsCareersGiving