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ID 16694

Video 33: Walter Gilbert, clip 1

Description:
Walter Gilbert is the Carl M. Loeb University Professor at Harvard University. In 1980, he won a Nobel Prize in Chemistry for his work on DNA sequencing.
Keywords:
nobel prize in chemistry, jacob and monod, walter gilbert, dna sequencing, harvard university, loeb, proteins
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Creative Commons License This work by Cold Spring Harbor Laboratory is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.

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16698. Video 33: Walter Gilbert, clip 5
Jacob and Monod never identified the inhibitor, but Gilbert found it.
16697. Video 33: Walter Gilbert, clip 4
How Jacob and Monod showed the existence of the inhibitor (what Gilbert calls the repressor).
16695. Video 33: Walter Gilbert, clip 2
Jacob and Monod discovered that genes control the amount of protein in a cell.
16700. Video 33: Walter Gilbert, clip 7
To explain their data, Jacob and Monod had to hypothesize the existence of mRNA.
16699. Video 33: Walter Gilbert, clip 6
What we know about gene regulation today.
16696. Video 33: Walter Gilbert, clip 3
Where did the idea of negative control come from?
16526. Biography 23: Frederick Sanger (1918- )
Frederick Sanger received two Nobel prizes (in the same category), for his work on protein sequencing and DNA sequencing.
15884. The lac operon
Francois Jacob and Jacques Monod figured out how bacteria controlled the production of an enzyme called beta-galactosidase. This system of feedback and negative regulation became the lac operon and was the first model for the control of protein productio
15927. Isolating DNA to make human insulin
Walter Gilbert's group tried to isolate the human insulin DNA sequence using the rat insulin DNA sequence.
16702. Biography 33: Francois Jacob (1920 - )
Francois Jacob and Jacques Monod were the first to discover how genes were turned on and off.
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