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ID 15916
DNA transformation
Description:
Stanley Cohen and Herbert Boyer inserted the recombinant DNA molecule they created into E. coli bacteria by means of a plasmid, thereby inducing the uptake and expression of a foreign DNA sequence known as "transformation."
Transcript:
Stanley Cohen and Herbert Boyer inserted the recombinant DNA molecule they created into E. coli bacteria by means of a plasmid, thereby inducing the uptake and expression of a foreign DNA sequence known as "transformation."
Keywords:
e coli bacteria,dna transformation,dna molecule,herbert boyer,stanley cohen,recombinant dna,dna sequence,e coli,plasmid,expression
This work by Cold Spring Harbor Laboratory is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.Related content:
- 16705. Animation 34: Genes can be moved between species.
- Stanley Cohen and Herbert Boyer transform bacteria with a recombinant plasmid, and Doug Hanahan studies induced transformation.
- SOURCE: DNAFTB
- 15074. Taking apart plasmid DNA, Stanley Cohen
- Stanley Cohen speaks about his and Herbert Boyer's experiment to make the first plasmid that had been engineered to contain foreign DNA.
- SOURCE: DNAi
- 16721. Biography 34: Herb W. Boyer (1936 - )
- Herb Boyer and Stan Cohen "invented" recombinant DNA technology.
- SOURCE: DNAFTB
- 15028. Interest in plasmids, Herbert Boyer
- Herb Boyer talks about Stanley Cohen's and his interest in plasmids as vectors for DNA.
- SOURCE: DNAi
- 15915. The first recombinant DNA
- Stanley Cohen and Herbert Boyer's historic experiment used techniques to cut and paste DNA to create the first custom-made organism containing recombined or "recombinant" DNA.
- SOURCE: DNAi
- 15626. Paul Berg and Stanley Cohen
- Herbert Boyer: Former varsity lineman turned biotech bigwig. Expert at cutting DNA before most people knew it could be done. Stanley Cohen: A born tinkerer; figured out the trick of using loops of DNA called plasmids to transform bacterial DNA
- SOURCE: DNAi
- 16720. Biography 34: Stan Norman Cohen (1935 - )
- Stan Cohen and Herb Boyer "invented" recombinant DNA technology.
- SOURCE: DNAFTB
- 15918. Transformation
- DNA transformation is a naturally occuring but rare event in which DNA can be transferred into bacteria. In 1970, Morton Mandel and Akiko Higa discovered a way to make E. coli more "competent" for transforming foreign DNA. Their calcium chloride method is
- SOURCE: DNAi
- 15162. Preparing the DNA for sequencing, Shane Yeager
- Shane Yeager, from the Whitehead Institute Center for Genome Research, explains the processes of storing and preparing DNA for sequencing.
- SOURCE: DNAi
- 15646. Herbert Boyer
- Image of Herbert Boyer. From lineman on the varsity football team to co-founder of the first biotech company, Boyer has never lacked imagination, drive, or vision. His and Stanley Cohen's recombinant DNA work paved the way for the biotech revolution.
- SOURCE: DNAi
