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ID 1169

COMT expression

Description:
Professor Daniel Weinberger explains that the schizophrenia candidate gene, COMT, is abundantly expressed in the hippocampus and prefrontal cortex.
Transcript:
Where is COMT expressed? So COMT is a gene that is turned on and off by the activity of a cell. And the cells that happen to have a lot of COMT in them are particularly the cells of the regions of the brain that are most implicated in schizophrenia - the prefrontal cortex and the hippocampal formation. And so nerve cells, neurons in these two parts of the brain, express, particularly abundantly, COMT.
Keywords:
COMT, gene, schizophrenia, expression, frontal, lobe, prefrontal, cortex, hippocampus, daniel, weinberger
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