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ID 1221

Development and Genetics

Professor Pat Levitt describes how developmental and genetic research contribute to brain architecture.
Developmental research and genetics research really are focusing on properties of what’s responsible for putting the brain together, for building the architecture. Developmental research is about trying to describe the events that occur as the brain gets assembled – kind of like describing how you build a house from bricks and mortar. Genetics is about understanding the bricks and mortar themselves. What are genes doing to contribute to building brain architecture and building development? We know that in addition to genetics, the development of the brain depends upon experience as well. It’s one of the unique properties of brain development that actually attracted me to it. So genes are important and experience is important in building this architecture.
development, developmental, genetic, research, brain, neurodevelopment, gene, pat, levitt
Creative Commons License This work by Cold Spring Harbor Laboratory is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.

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1226. Toxic Stress
Professor Pat Levitt defines toxic stress, a term used by neurobiologists to describe negative experiences that can affect brain development.
1228. Neurodevelopment and Experience
Professor Pat Levitt likens the brain to a rosebush, where the developing nervous system needs pruning and maintenance to function optimally.
1222. Autism - Early Diagnosis
Professor Pat Levitt explains that the sooner autism is diagnosed, the more effective the intervention.
1231. Progenitor Cells and Cell Fate
Professor Pat Levitt explains that progenitor cells express transcription factors that determine whether the cell becomes a neuron.
1230. Progenitor Cells
Professor Pat Levitt describes progenitor cells, which are immature, undifferentiated cells. They are the precursors to neurons.
1225. Schizophrenia - Genetic Vulnerability
Professor Pat Levitt comments that people with genetic vulnerability to schizophrenia often have developmental problems from an early age.
1229. ADHD Genes
Professor Pat Levitt explains that the genetic basis for ADHD is evident from twin and family studies.
1232. Progenitor Cells - Manipulation
Professor Pat Levitt describes how progenitor cells can be manipulated to develop into a particular type of neuron.
1224. Schizophrenia - Early Symptoms
Professor Pat Levitt explains that while schizophrenia is rarely seen in childhood, there are early signs of developmental problems.
1223. Genes and Schizophrenia
Professor Pat Levitt discusses that although it shares genes with other disorders, schizophrenia is likely caused by unique combinations of genes.
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