Website Search
ID 15159

Sequencing mitochondrial DNA, Frederick Sanger

Interviewee: Frederick Sanger. Frederick Sanger talks about the results from sequencing human mitochondrial DNA. (DNAi Location:Manipulation > Techniques > Sorting and sequencing > Interviews > Sequencing mitochondrial DNA)
And one interesting thing we found was that the genetic code was different in the mitochondria from what it was in the rest of the human body, which was quite important. And of course, the actual sequence of the, we got the sequence of the DNA and from that you can work out the sequence of the few proteins that are made. And the sequence of those proteins varies considerably from individual, one individual to another, so one outcome was a method for tracing people's ancestry and, in criminal problems, you can identify differences in DNA of people.
human mitochondrial dna,sanger sequencing,frederick sanger,manipulation techniques,dna sequencing,dnai,genetic code,interviewee,mitochondria,human body,proteins,ancestry
Creative Commons License This work by Cold Spring Harbor Laboratory is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.

Related content:

15160. Sequencing proteins and DNA, Frederick Sanger
Frederick Sanger talks about the differences between sequencing proteins and sequencing DNA.
15479. Sanger method of DNA sequencing, 3D animation with narration
The DNA sequencing method developed by Fred Sanger forms the basis of automated "cycle" sequencing reactions today.
15161. Computers and sequencing, Frederick Sanger
Frederick Sanger describes the use of computers in sequencing.
16526. Biography 23: Frederick Sanger (1918- )
Frederick Sanger received two Nobel prizes (in the same category), for his work on protein sequencing and DNA sequencing.
15098. Making sequencing automated, Michael Hunkpiller
Michael Hunkapiller talks about the process of developing the automated sequencing machine.
15567. DNA sequence
Early sequencers used four different reactions to determine the placement of each of DNA's four bases - known as A, C, T & G - in the sequence.
15922. Early DNA sequencing
Two sequencing techniques were developed independently in the 1970s. The method developed by Fred Sanger used chemically altered "dideoxy" bases to terminate newly synthesized DNA fragments at specific bases (either A, C, T, or G). These fragments are th
16036. Fred Sanger, 1975
A gene is a discrete sequence of DNA nucleotides
15179. Mitochondria from the beginning, Douglas Wallace
Molecular geneticist Douglas Wallace talks about the origin of our mitochondria and the DNA within.
15979. A mitochondrial DNA sequence
Human mitochondrial DNA is 16,569 base pairs in length.
Cold Spring Harbor Laboratory
CSHL HomeAbout CSHLResearchEducationPublic EventsNewsstandPartner With UsGiving