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ID 15676

DNA helix

In 1953, Watson and Crick published a paper: A Structure for Deoxyribose Nucleic Acid. Based on available data from X-ray diffraction patterns and 3D conceptualization through model building, Watson and Crick proposed that DNA is a double helix - a twisted ladder - with two phosphate-based backbones and "runged" nucleotides that pair. Their paper ended with this comment: It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copying mechanism for the genetic material.
x ray diffraction,watson and crick,dna helix,diffraction patterns,double helix,james watson,model building,conceptualization,backbones,genetic material,nucleotides,nucleic acid,phosphate,ladder
Creative Commons License This work by Cold Spring Harbor Laboratory is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 United States License.

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16422. Animation 19: The DNA molecule is shaped like a twisted ladder.
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16421. Concept 19: The DNA molecule is shaped like a twisted ladder.
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15874. Franklin's X-ray
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15539. DNA base pairs
DNA base pairs
15015. Francis Crick and James Watson in Cambridge.
1953 picture of Francis Crick (L) and James Watson (R) walking along the backs of King's College in Cambridge.
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