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The Glutamate System

Description:
Professor Trevor Robbins describes some of the key functions of the excitatory glutamate system, which is integral to information processing and long term potentiation.
Transcript:
The glutamate system of the brain, again it is one of the two major amino acid systems, GABA being the other major one. The glutamate system is a fast-signaling system that is very important for information processing in neuronal networks of the neocortex and hippocampus in particular. Glutamate is very much involved in the process of long-term potentiation, which is a neuronal model of memory. There are at least three major types of glutamate receptors: the AMPA receptor, the NMDA receptor, and the kainate receptor. Some people think that we will discover memory-enhancing drugs by using agents that work at these receptors, one example being the so-called ampakines.
Keywords:
glutamate, glutamergic, receptors, long, term, potentiation, neurotransmitter, hippocampus, nmda, gaba, AMPA, kainate, receptor, signaling, ampakine, trevor, robbins,
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