The Glutamate System
Professor Trevor Robbins describes some of the key functions of the excitatory glutamate system, which is integral to information processing and long term potentiation.
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Professor Graham Collingridge describes the roles played by NMDA and AMPA receptors in long-term potentiation (LTP).
1151. GABA (Gamma-aminobutyric Acid)
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2141. Glutamate uptake decreased in Alzheimer's disease
Professor Dennis Selkoe discusses the finding that amyloid beta seems to decrease the uptake of glutamate by synapses.
1173. Glutamate and Schizophrenia
Professor Daniel Weinberger discusses evidence from a number of research areas that highlight the importance of the neurotransmitter glutamate in schizophrenia.
1100. Glutamate Receptors
Professor Graham Collingridge describes the glutamate receptor, AMPA, the workhorse receptor for communicating information.
1277. Molecules for Memory
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1109. NMDA Receptors, Multi-protein Complexes, & LTP
Professor Tom O'Dell describes the role played by NMDA receptors, as part of a large multi-protein complex, in facilitating long-term potentiation (LTP).
1439. Biochemicals - Excitation and Inhibition
Doctor Josh Dubnau explains that the genes active in different neurons can make them excitatory (e.g. glutamate) or inhibitory (e.g. GABA). These neurotransmitters are critical to learning.
1997. Learning and memory
Learning and memory are two intimately linked cognitive processes that stem from interactions with the environment (experience).
1211. What is NMDA?
Professor Seth Grant explains that NMDA is an amino acid derivative very similar to glutamate - the brain's primary excitatory neurotransmitter.