Long-term Potentiation

Professor Graham Collingridge describes the process of long-term potentiation (LTP) - the process by which synapses increase their efficiency.

LTP is the process by which synapses increase their efficiency. The idea is that if something is important the synapses are used a lot, and they remember that by changing their properties. That is the way information that is important is stored in the brain.

ltp, long, term, potentiation, efficiency, synapse, graham, collingridge

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1101. AMPA and NMDA Receptors

Professor Graham Collingridge describes the roles played by NMDA and AMPA receptors in long-term potentiation (LTP).

  • ID: 1101
  • Source: G2C

1099. Long-term Depression

Professor Graham Collingridge describes the process of long-term depression (LTD), a way of decreasing the efficiency of synaptic transmission.

  • ID: 1099
  • Source: G2C

1100. Glutamate Receptors

Professor Graham Collingridge describes the glutamate receptor, AMPA, the workhorse receptor for communicating information.

  • ID: 1100
  • Source: G2C

1107. Depotentiation

Professor Tom O'Dell defines depotentiation - the erasure of long-term potentiation (LTP) at the synapse.

  • ID: 1107
  • Source: G2C

549. Long-term Potentiation

Long-term Potentiation of synaptic transmission is commonly referred to as LTP. It can be recorded in many parts of the nervous system, but is very widely studied in the hippocampus.

  • ID: 549
  • Source: G2C

2037. Synapse changes during learning

Professor Kenneth Kosik discusses changes in synapses that accompany long-term potentiation, which include enlarged dendritic spines.

  • ID: 2037
  • Source: G2C

1102. NMDA Receptor and Learning (2)

Professor Graham Collingridge briefly describes how the NMDA receptor facilitates Hebbian learning (a mechanism of synaptic plasticity).

  • ID: 1102
  • Source: G2C

1097. Synaptic Plasticity (2)

Professor Graham Collingridge explains that synaptic plasticity is the way most information is stored in the central nervous system.

  • ID: 1097
  • Source: G2C

1108. Synaptic Plasticity (1)

Professor Tom O'Dell discusses synaptic plasticity - the strengthening and weakening of synaptic connections between neurons.

  • ID: 1108
  • Source: G2C

1210. Long-term Potentiation and Learning

Professor Seth Grant discusses the complicated relationship between long-term potentiation and learning/memory.

  • ID: 1210
  • Source: G2C